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Try not to blink and do not rub your eye after putting the drop Apply a drop of Lumigan in your eyes, as prescribed by the doctor. Bimatoprost lowers intraocular pressure in patients by increasing the outflow of aqueous humor through the trabecular network and uveoscleral outflow. Try not to blink and do not rub your eye after putting the drop Lumigan Eye Drops or Bimatoprost are used to treat high pressure inside the eye due to glaucoma or other eye diseases such as ocular hypertension. After you feel the eye drop, gently close your eyes for 1 to 2 minutes. My doctor doesn't approve but can't give me a good reason why it should be applied before bedtime, as it's obviously working well Rajive Goel 14 July 2010. Lumigan is a prostaglandin eye drop that helps drain fluid and release pressure from inside the eye. 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